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Human papilloma virus (HPV) found in most actinic keratoses (AK) & squamous cell carcinomas (SCC)

A leading dermatologist-researcher Dr. Eggert Stockfleth and his lab in Berlin has demonstrated that HPV 21 can be found in 95% of actinic keratoses (AK) and 100% of squamous cell carcinomas (SCC); less commonly, HPV 5 & 8 have also been associated. The need for immunomodulation using agents such as topical imiquimod (long ago approved for treating HPV) for these lesions makes even more sense now.

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